PR-INBRE current cycle publications

99 entries « 1 of 2 »

2024

Novel inhibition of central carbon metabolism pathways by Rac and Cdc42 inhibitor MBQ-167 and paclitaxel

AM, Cruz-Collazo; O, Katsara; N, Grafals-Ruiz; J, Colon Gonzalez; S, Dorta-Estremera; VP, Carlo; N, Chorna; RJ, Schneider; S, Dharmawardhane

Novel inhibition of central carbon metabolism pathways by Rac and Cdc42 inhibitor MBQ-167 and paclitaxel

In: Mol Cancer Ther, 2024.

Links

Shifts in the gut microbiota of sea urchin Diadema antillarumassociated with the 2022 disease outbreak

Shifts in the gut microbiota of sea urchin Diadema antillarumassociated with the 2022 disease outbreak

In: Front Microbiology, 2024.

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Synthesis of the Novel N-(2-Hexadecynoyl)-l-Homoserine Lactone and Evaluation of Its Antiquorum Sensing Activity in Chromobacterium violaceum

DJ, Sanabria-Ríos; R, García-Del-Valle; S, Bosh-Fonseca; J, González-Pagán; A, Díaz-Rosa; K, Acevedo-Rosario; L, Reyes-Vicente; A, Colom; NM, Carballeira

Synthesis of the Novel N-(2-Hexadecynoyl)-l-Homoserine Lactone and Evaluation of Its Antiquorum Sensing Activity in Chromobacterium violaceum

In: ACS Omega, 2024.

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Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

JG, Medina-Feliciano; G, Valentín-Tirado; K, Luna-Martínez; Y, Miranda-Negrón; JE, García-Arrarás

Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

In: bioRxiv, 2024.

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 After an initial Hermansky-Pudlak syndrome clinical diagnosis, molecular testing reveals variants for oculocutaneous albinism type 1B: A case report

J, Serrano-González; I, Montes-Rodríguez; JY, Renta; R, Rojas; CL, Cadilla

After an initial Hermansky-Pudlak syndrome clinical diagnosis, molecular testing reveals variants for oculocutaneous albinism type 1B: A case report

In: Mol Genet Genomic Med, 2024.

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 Immune and Microbial Signatures Associated with PD-1 Blockade Sensitivity in a Preclinical Model for HPV+ Oropharyngeal Cancer

J, Díaz-Rivera; MA, Rodríguez-Rivera; NM, Meléndez-Vázquez; F, Godoy-Vitorino; SM, Dorta-Estremera

Immune and Microbial Signatures Associated with PD-1 Blockade Sensitivity in a Preclinical Model for HPV+ Oropharyngeal Cancer

In: Cancers (Basel), 2024.

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Unraveling the Impact of Six Pentacyclic Triterpenes Regulating Metabolic Pathways on Lung Carcinoma Cells

A, Torres-Sanchez; G, Torres; S, Estrada; D, Perez; C, Garcia; M, Milian; E, Velazquez; V, Molina; Y, Delgado

Unraveling the Impact of Six Pentacyclic Triterpenes Regulating Metabolic Pathways on Lung Carcinoma Cells

In: Pharmaceuticals (Basel), 2024.

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Development of a Neuropeptide Y-Sensitive Implantable Microelectrode for Continuous Measurements

L, Fernández-Vega; Meléndez-Rodríguez D and, Ospina-Alejandro M; K, Casanova; Y, Vázquez; L, Cunci

Development of a Neuropeptide Y-Sensitive Implantable Microelectrode for Continuous Measurements

In: ACS Sens., 2024.

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Plasma Proteins Associated with COVID-19 Severity in Puerto Rico

LJ, Rosario-Rodríguez; YM, Cantres-Rosario; K, Carrasquillo-Carrión; A, Rosa-Díaz; AE, Rodríguez-De Jesús; V, Rivera-Nieves; EL, Tosado-Rodríguez; LB, Méndez; A, Roche-Lima; J, Bertrán; LM, Meléndez

Plasma Proteins Associated with COVID-19 Severity in Puerto Rico

In: Int J Mol Sci, 2024.

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 Extracts Induce INFγ-Independent Activation of CIITA, MHCII, and Increases Inflammation in Human Bronchial Epithelium

H, Jirau-Colón; BD, Jiménez-Vélez

Extracts Induce INFγ-Independent Activation of CIITA, MHCII, and Increases Inflammation in Human Bronchial Epithelium

In: Toxics, 2024.

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New Regulatory roles for Human Serum Amyloid A

CG, García-Cortés; E, Parés-Matos

New Regulatory roles for Human Serum Amyloid A

In: 2024.

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Improved LINE-1 Detection through Pattern Matching by Increasing Probe Length

JO, López; Quiñones J and, Martínez ED

Improved LINE-1 Detection through Pattern Matching by Increasing Probe Length

In: Biology (Basel), 2024.

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Advancing Primary Ciliary Dyskinesia Diagnosis through High-Speed Video Microscopy Analysis

W, De Jesús-Rojas; ZJ, Demetriou; J, Muñiz-Hernández; G, Rosario-Ortiz; FM, Quiñones; MJ, Ramos-Benitez; RA, Mosquera

Advancing Primary Ciliary Dyskinesia Diagnosis through High-Speed Video Microscopy Analysis

In: Cells, 2024.

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 Vaginal Microbiota and HPV in Latin America: A Narrative Review

E, Tosado-Rodríguez; I, Alvarado-Vélez; J, Romaguera; F, Godoy-Vitorino

Vaginal Microbiota and HPV in Latin America: A Narrative Review

In: Microorganisms, 2024.

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Gut microbiota composition is associated with the efficacy of Delta-24-RGDOX in malignant gliomas

NM, Meléndez-Vázquez; TT, Nguyen; X, Fan; AR, López-Rivas; J, Fueyo; C, Gomez-Manzano; F, Godoy-Vitorino

Gut microbiota composition is associated with the efficacy of Delta-24-RGDOX in malignant gliomas

In: Mol Ther Oncol, 2024.

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Ecological competition in the oral mycobiome of Hispanic adults living in Puerto Rico associates with periodontitis

Acosta-Pagán, Kimil; Bolaños-Rosero, Benjamín; Pérez, Cynthia; Ortíz, Ana P.; Godoy-Vitorino, Filipa

Ecological competition in the oral mycobiome of Hispanic adults living in Puerto Rico associates with periodontitis

In: Journal of Oral Microbiology, 2024.

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Measurement of neuropeptide Y with molecularly imprinted polypyrrole on carbon fiber microelectrodes

L, López; K, Lozano; J, Cruz; K, Flores; L, Fernández-Vega; L, Cunci

Measurement of neuropeptide Y with molecularly imprinted polypyrrole on carbon fiber microelectrodes

In: Neuropeptides, 2024.

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Exploring the interplay between running exercises, microbial diversity, and tryptophan metabolism along the microbiota-gut-brain axis

A, Vazquez-Medina; N, Rodriguez-Trujillo; K, Ayuso-Rodriguez; F, Marini-Martinez; R, Angeli-Morales; G, Caussade-Silvestrini; F, Godoy-Vitorino; N, Chorna

Exploring the interplay between running exercises, microbial diversity, and tryptophan metabolism along the microbiota-gut-brain axis

In: 2024.

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Estradiol reduction through aromatase inhibition impairs cocaine seeking in male rats

JK, Alvarado-Torres; R, Morales-Silva; de Leon A, Sanabria Ponce; G, Rodriguez-Torres; J, Perez-Torres; Y, Perez-Perez; D, Mueller; MT, Sepulveda-Orengo

Estradiol reduction through aromatase inhibition impairs cocaine seeking in male rats

In: Front Behav Neuroscience, 2024.

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 Identification of the native Torpedo californica nicotinic acetylcholine receptor’s glycan composition after a multi-step sequential purification method using MALDI-ToF MS

R, Maldonado-Hernández; Quesada,; JA, González-Feliciano; A, Baerga-Ortiz; JA, Lasalde-Dominicci

Identification of the native Torpedo californica nicotinic acetylcholine receptor’s glycan composition after a multi-step sequential purification method using MALDI-ToF MS

In: Proteomics 2024, 2024.

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Mechanistics of pH-Dependent Sulfmyoglobin Formation: Spin Control and His64 Proton Relay

Mackenzie, A.; Santos, L.; Arbelo, H.; Wymore, T.; Garriga, J.

Mechanistics of pH-Dependent Sulfmyoglobin Formation: Spin Control and His64 Proton Relay

In: Journal of Chemistry, vol. 2024, 2024.

Links

2023

In vitro generation of murine myeloid-derived suppressor cells from hematopoietic progenitor cells

LM, Hernandez-Delgado; A, Laboy-Figueroa; A, Lopez-Velazquez; C, Flores-Ortiz; K, Alicea-Torres

In vitro generation of murine myeloid-derived suppressor cells from hematopoietic progenitor cells

In: Methods Cell Biol, 2023.

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Inflammatory cytokines and a diverse cervicovaginal microbiota associate with cervical dysplasia in a cohort of Hispanics living in Puerto Rico

E, Tosado-Rodríguez; LB, Mendez; AM, Espino; S, Dorta-Estremera; EE, Aquino; J, Romaguera; F, Godoy-Vitorino

Inflammatory cytokines and a diverse cervicovaginal microbiota associate with cervical dysplasia in a cohort of Hispanics living in Puerto Rico

In: 2023.

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Prioritizing cardiovascular disease-associated variants altering NKX2-5 and TBX5 binding through an integrative computational approach

EG, Peña-Martínez; DA, Pomales-Matos; A, Rivera-Madera; JL, Messon-Bird; JG, Medina-Feliciano; L, Sanabria-Alberto; AC, Barreiro-Rosario; J, Rivera-Del Valle; JM, Rodríguez-Ríos; JA, Rodríguez-Martínez

Prioritizing cardiovascular disease-associated variants altering NKX2-5 and TBX5 binding through an integrative computational approach

In: J Biol Chem, 2023.

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Determining the Safety of the Tobacco Cembranoid (1S,2E,4R,6R,7E,11E)-Cembratriene-4,6-diol (4R): A Translational Study in Nonhuman Primates

N, Sabeva; W, Castro; Y, Ferrer-Acosta; P.A, Ferchmin; V.A, Eterovic; D, Sierra-Mercado; N, Pérez-Rios; S, Rivas-Tumanyan; A.H, Martins

Determining the Safety of the Tobacco Cembranoid (1S,2E,4R,6R,7E,11E)-Cembratriene-4,6-diol (4R): A Translational Study in Nonhuman Primates

In: 2023.

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Edible flora in pre-Columbian Caribbean coprolites: Expected and unexpected data

J, Reynoso-García; TM, Santiago-Rodriguez; Y, Narganes-Storde; RJ, Cano; GA, Toranzos

Edible flora in pre-Columbian Caribbean coprolites: Expected and unexpected data

In: PLoS One, 2023.

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Unraveling the functional dark matter through global metagenomics

GA, Pavlopoulos; FA, Baltoumas; S, Liu; O, Selvitopi; AP, Camargo; S, Nayfach; A, Azad; S, Roux; L, Call; NN, Ivanova; IM, Chen; D, Paez-Espino; E, Karatzas; Consortium, Novel Metagenome Protein Families; I, Iliopoulos; K, Konstantinidis; JM, Tiedje; J, Pett-Ridge; D, Baker; A, Visel; CA, Ouzounis; S, Ovchinnikov; A, Buluç; NC, Kyrpides

Unraveling the functional dark matter through global metagenomics

In: Nature, 2023.

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Evolutionary dynamics of genome size and content during the adaptive radiation of Heliconiini butterflies

F, Cicconardi; E, Milanetti; de Castro EC, Pinheiro; A, Mazo-Vargas; SM, Van Belleghem; AA, Ruggieri; P, Rastas; J, Hanly; E, Evans; CD, Jiggins; W, Owen McMillan; R, Papa; D, Di Marino; A, Martin; SH, Montgomery

Evolutionary dynamics of genome size and content during the adaptive radiation of Heliconiini butterflies

In: Nat Commun, 2023.

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The Characterization and Evaluation of the Soluble Triggering Receptor Expressed on Myeloid Cells-like Transcript-1 in Stable Coronary Artery Disease

Z, Bayrón-Marrero; S, Branfield; J, Menéndez-Pérez; Nieves-López B, Ospina L; Y, Cantres-Rosario; LM, Melendez; R, Hunter; A, Gibson; G, Maldonado-Martínez; AV, Washington

The Characterization and Evaluation of the Soluble Triggering Receptor Expressed on Myeloid Cells-like Transcript-1 in Stable Coronary Artery Disease

In: Int J Mol Sci., 2023.

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The cervical microbiota of Hispanics living in Puerto Rico is nonoptimal regardless of HPV status

D, Vargas-Robles; J, Romaguera; I, Alvarado-Velez; E, Tosado-Rodríguez; A, Dominicci-Maura; M, Sanchez; KJ, Wiggin; M, Martinez-Ferrer; JA, Gilbert; LJ, Forney; F, Godoy-Vitorino

The cervical microbiota of Hispanics living in Puerto Rico is nonoptimal regardless of HPV status

In: mSystems, 2023.

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Mechanisms of Regulation of the CHRDL1 Gene by the TWIST2 and ADD1/SREBP1c Transcription Factors

JJ, Casasnovas-Nieves; Y, Rodríguez; HL, Franco; CL, Cadilla

Mechanisms of Regulation of the CHRDL1 Gene by the TWIST2 and ADD1/SREBP1c Transcription Factors

In: Genes (Basel), 2023.

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Synergistic interactions of cytarabine-adavosertib in leukemic cell lines proliferation and metabolomic endpoints

GO, Rodríguez-Vázquez; AO, Diaz-Quiñones; N, Chorna; IK, Salgado-Villanueva; J, Tang; WIS, Ortiz; HM, Maldonado

Synergistic interactions of cytarabine-adavosertib in leukemic cell lines proliferation and metabolomic endpoints

In: Biomed Pharmacother, 2023.

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Substrate topographies modulate the secretory activity of human bone marrow mesenchymal stem cells

H, Rosado-Galindo; M, Domenech

Substrate topographies modulate the secretory activity of human bone marrow mesenchymal stem cells

In: Stem Cell Res Ther, 2023.

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Assessment of Vibrio populations in a transect of Rhizophora mangle in Punta Galeta, Panamá: culture-dependent analyses reveal biotechnological applications

J, Sánchez-Gallego; L, Atencio; J, Pérez; O, Dupuy; E, Díaz-Ferguson; F, Godoy-Vitorino

Assessment of Vibrio populations in a transect of Rhizophora mangle in Punta Galeta, Panamá: culture-dependent analyses reveal biotechnological applications

In: Rev Biol Trop, 2023.

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Oncogenic Proteomics Approaches for Translational Research and HIV-Associated Malignancy Mechanisms

E, Alvarez-Rivera; EJ, Ortiz-Hernández; E, Lugo; LM, Lozada-Reyes; NM, Boukli

Oncogenic Proteomics Approaches for Translational Research and HIV-Associated Malignancy Mechanisms

In: Proteomes, 2023.

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Comparison Between Bayesian and Frequentist Tail Probability Estimates

Shen, Nan; González-Arévalo, Bárbara; Pericchi, Luis Raúl

Comparison Between Bayesian and Frequentist Tail Probability Estimates

In: N Engl J STAT DATA SCI, 2023.

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Rac and Cdc42 inhibitors reduce macrophage function in breast cancer preclinical models

A, Torres-Sanchez; M, Rivera-Robles; L, Castillo-Pichardo; M, Martínez-Ferrer; SM, Dorta-Estremera; S, Dharmawardhane

Rac and Cdc42 inhibitors reduce macrophage function in breast cancer preclinical models

In: Front Oncol., 2023.

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The Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancer

Crespo GV, Ortiz J; EH, O'Farrill; CP, Vlaar; M, Inyushin; Y, Kucheryavykh; L, Kucheryavykh

The Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancer

2023.

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Gut microbiota variation of a tropical oil-collecting bee species far exceeds that of the honeybee

Kardas E,; AM, González-Rosario; T, Giray; JD, Ackerman; F, Godoy-Vitorino

Gut microbiota variation of a tropical oil-collecting bee species far exceeds that of the honeybee

In: Front Microbiol, 2023.

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SARS-CoV-2 Omicron Replacement of Delta as Predominant Variant, Puerto Rico

GA, Santiago; HR, Volkman; B, Flores; GL, González; KN, Charriez; LC, Huertas; SM, Van Belleghem; V, Rivera-Amill; C, Major; C, Colon; R, Tosado; LE, Adams; M, Marzán; L, Hernández; I, Cardona; E, O'Neill; G, Paz-Bailey; R, Papa; JL, Muñoz-Jordan

SARS-CoV-2 Omicron Replacement of Delta as Predominant Variant, Puerto Rico

In: Emerg Infect Dis., 2023.

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The Effects of Amyloid-β on Metabolomic Profiles of Cardiomyocytes and Coronary Endothelial Cells

S, Jang; N, Chorna; KM, Rodríguez-Graciani; M, Inyushin; S, Fossati; S, Javadov

The Effects of Amyloid-β on Metabolomic Profiles of Cardiomyocytes and Coronary Endothelial Cells

In: J Alzheimers Dis., 2023.

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The Antiviral Compound PSP Inhibits HIV-1 Entry via PKR-Dependent Activation in Monocytic Cells

E, Alvarez-Rivera; M, Rodríguez-Valentín; NM, Boukli

The Antiviral Compound PSP Inhibits HIV-1 Entry via PKR-Dependent Activation in Monocytic Cells

In: Viruses, 2023.

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High level of novelty under the hood of convergent evolution

SM, Van Belleghem; AA, Ruggieri; C, Concha; L, Livraghi; L, Hebberecht; ES, Rivera; JG, Ogilvie; JJ, Hanly; IA, Warren; S, Planas; Y, Ortiz-Ruiz; R, Reed; JJ, Lewis; CD, Jiggins; BA, Counterman; WO, McMillan; R, Papa

High level of novelty under the hood of convergent evolution

In: 2023.

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Surface roughness modulates EGFR signaling and stemness of triple-negative breast cancer cells

H, Rosado-Galindo; M, Domenech

Surface roughness modulates EGFR signaling and stemness of triple-negative breast cancer cells

In: Front Cell Dev Biol, 2023.

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Metadherin Regulates Inflammatory Breast Cancer Invasion and Metastasis

G, Ortiz-Soto; NS, Babilonia-Díaz; MY, Lacourt-Ventura; DM, Rivera-Rodríguez; JI, Quiñones-Rodríguez; M, Colón-Vargas; I, Almodóvar-Rivera; LE, Ferrer-Torres; IJ, Suárez-Arroyo; MM, Martínez-Montemayor

Metadherin Regulates Inflammatory Breast Cancer Invasion and Metastasis

In: Int J Mol Sci. 2023, 2023.

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Purinergic P2X7 receptor-mediated inflammation precedes PTSD-related behaviors in rats

O, Torres-Rodríguez; Y, Rivera-Escobales; Y, Castillo-Ocampo; B, Velazquez; M, Colón; JT, Porter

Purinergic P2X7 receptor-mediated inflammation precedes PTSD-related behaviors in rats

In: Brain Behav Immun, 2023.

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The PYK2 inhibitor PF-562271 enhances the effect of temozolomide on tumor growth in a C57Bl/6-Gl261 mouse glioma model

J, Ortiz-Rivera; R, Nuñez; Y, Kucheryavykh; L, Kucheryavykh

The PYK2 inhibitor PF-562271 enhances the effect of temozolomide on tumor growth in a C57Bl/6-Gl261 mouse glioma model

In: J Neurooncol, 2023.

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Bacterial characterization of digestive tract of the Horned Screamer (Anhima cornuta), a tropical herbivorous “unicorn” bird

M., García-Amado; C., Rudolf; M., Fuentes-Fuentes; M., Martínez; N., Chorna; F, Godoy-Vitorino

Bacterial characterization of digestive tract of the Horned Screamer (Anhima cornuta), a tropical herbivorous “unicorn” bird

In: PeerJ 11:e14805, 2023.

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 The Epibiotic Microbiota of Wild Caribbean Sea Urchin Spines Is Species Specific

R, Rodríguez-Barreras; A, Dominicci-Maura; EL, Tosado-Rodríguez; F, Godoy-Vitorino

The Epibiotic Microbiota of Wild Caribbean Sea Urchin Spines Is Species Specific

In: 2023.

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Characterization and Expression of Holothurian Wnt Signaling Genes during Adult Intestinal Organogenesis

Auger, Noah A.; Medina-Feliciano, Joshua G.; David J. Quispe-Parra ORCID, Stephanie Colón-Marrero; January 25 José E. García-Arrarás., 2023

Characterization and Expression of Holothurian Wnt Signaling Genes during Adult Intestinal Organogenesis

In: Genes 2023, 2023.

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