PR-INBRE current cycle publications

139 entries « 1 of 3 »

2025

Clinical Symptom Patterns as Predictors of SARS-CoV-2 Infection in Healthcare Workers in Puerto Rico

Ortiz DV, Romaguera J; JL, Santos Agrait; F, Vázquez; ME, Pérez; CD, Zorrilla; F, Godoy-Vitorino

Clinical Symptom Patterns as Predictors of SARS-CoV-2 Infection in Healthcare Workers in Puerto Rico

In: Int J Environ Res Public Health, 2025.

Links

WntA expression and wing transcriptomics illuminate the evolution of stripe patterns in skipper butterflies

JD, Alqassar; TS, Rivera-Miranda; JJ, Hanly; CR, Day; SM, Planas Soto-Navarro; PB, Frandsen; Papa R, Martin A

WntA expression and wing transcriptomics illuminate the evolution of stripe patterns in skipper butterflies

In: Biol Open, 2025.

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Selenium Adsorption on the (111), (100), (110) and (211) surfaces of Face-Centered-Cubic Metals: Density Functional Calculations of the Potential Energy Surfaces

RLA, Rivera; YL, Colon-Ruiz; A, De La Torre-Rosa; AI, Garcia-Ramos; AM, Garcia-Sanchez; L, Gierbolini-Ortiz; M, Lopez-Torres; N, Ortiz-Rodriguez; VA, Rivera-Rivera; SC, Santiago-Soler; JA, Siberon-Albertorio; JN, Silva-Burgos; C, Torres-Morales; JA, Santana

Selenium Adsorption on the (111), (100), (110) and (211) surfaces of Face-Centered-Cubic Metals: Density Functional Calculations of the Potential Energy Surfaces

In: Chemistry Select, 2025.

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Molecular and culture-based identification of Aspergillus species in water-impacted homes following Hurricane María in Puerto Rico

LN, Vélez-Torres; B, Bolaños-Rosero; Godoy-Vitorino,; FE, Rivera-Mariani; JP, Maestre; K, Kinney; H, Cavallin-Calanche

Molecular and culture-based identification of Aspergillus species in water-impacted homes following Hurricane María in Puerto Rico

In: Sci Rep, 2025.

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Air Pollutants in Puerto Rico: Key Pollutants and Carcinogenic Properties

D, Kaya; C, Santiago; E, Pernas; S, Truong; G, Martinez; LB, Méndez; Y, Delgado

Air Pollutants in Puerto Rico: Key Pollutants and Carcinogenic Properties

In: Int J Environ Res Public Health, 2025.

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Congenital heart disease missense mutations in the TBX5 DNA-binding domain alter thermal stability and DNA-binding affinity

A, Rivera-Madera; EG, Peña-Martínez; JL, Messon-Bird; DA, Pomales-Matos; OL, Echevarría-Bonilla; L, Sanabria-Alberto; EA, Peterson-Peguero; JA, Rodríguez-Martínez

Congenital heart disease missense mutations in the TBX5 DNA-binding domain alter thermal stability and DNA-binding affinity

In: G3 (Bethesda), 2025.

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The Effect of Cefazolin on the Gut Microbiome of Female Rats After Spinal Cord Injury

LH, Pagán-Rivera; F, Godoy-Vitorino; NM, Meléndez-Vázquez; SE, Ocasio-Rivera; ME, Santiago-Gascot; JM, Santiago; I, Salgado; V, González; O, Martínez-Guzmán; M, Cáceres-Chacón; A, Torrado-Tapias; JD, Miranda

The Effect of Cefazolin on the Gut Microbiome of Female Rats After Spinal Cord Injury

In: Microorganisms, 2025.

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Role of Glyoxalase in Astrocytes' Supportive Function Under Hyperglycemic Conditions: Aminoguanidine and Kir4.1 Channel Recovery

J, Colón-Vázquez; NM, Rosado-Rivera; JJ, Navedo-Jackson; AA, Angueira-Laureano; Y, Hernandez-Santiago; G, Maldonado-Martinez; MP, Méndez-González; MJ, Eaton; SN, Skatchkov; DE, Rivera-Aponte

Role of Glyoxalase in Astrocytes' Supportive Function Under Hyperglycemic Conditions: Aminoguanidine and Kir4.1 Channel Recovery

In: Brain Sci, 2025.

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Speaking science in a fractured world: making truth land when facts alone cannot

RM, Calisi-Rodríguez; K, Alicea-Torres; JC, Peng; NA, Theodosiou; CD, Rogers

Speaking science in a fractured world: making truth land when facts alone cannot

In: Development, 2025.

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Connecting Innovation and Trust through Translational Sciences - A Need for a Community Focus and Effective Education Strategies

F, Godoy-Vitorino; M, Borrero; J, Pérez-Santiago; R, García-García; C, Gomez-Manzano

Connecting Innovation and Trust through Translational Sciences - A Need for a Community Focus and Effective Education Strategies

In: Health Sci J, 2025.

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Strengthening Integrative Microbiome Research Through Regional Leadership

F, Godoy-Vitorino

Strengthening Integrative Microbiome Research Through Regional Leadership

In: Int J Environ Res Public Health, 2025.

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Gut microbiota distinguishes aging hispanics with Alzheimer's disease: associations with cognitive impairment and severity

V, Sepúlveda-Rivera; G, Olivieri-Henry; H, Morales-González; J, Ruiz-Adames; C, Herrero-Rivera; A, Rentas-Echeverria; V, Cardona-Berdecia; C, Soler-Llompart; AC, Sala-Morales; G, Pérez-Montero; E, Blanco-Ruiz; F, Godoy-Vitorino

Gut microbiota distinguishes aging hispanics with Alzheimer's disease: associations with cognitive impairment and severity

In: Sci Rep, 2025.

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RSPH4A-PCDx: An Index to Predict Lung Function Decline in Primary Ciliary Dyskinesia

G, Román-Ríos; G, Rosario-Ortiz; MJ, Ramos-Benitez; RA, Mosquera; W, De Jesús-Rojas

RSPH4A-PCDx: An Index to Predict Lung Function Decline in Primary Ciliary Dyskinesia

In: Adv Respir Med, 2025.

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Determining the role of FAP1 in S. cerevisiae, cultivated in Nitrogen-limited media

MM, Fajardo; EIP, Matos

Determining the role of FAP1 in S. cerevisiae, cultivated in Nitrogen-limited media

In: Int J Mol Biol Open Access, 2025.

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Challenges and Opportunities: Interplay between Infectious Disease and Antimicrobial Resistance in Medical Device Surface Applications

V, Ortiz-Gómez; R, Maldonado-Hernández

Challenges and Opportunities: Interplay between Infectious Disease and Antimicrobial Resistance in Medical Device Surface Applications

In: ACS Omega, 2025.

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Age-related neutrophil activation in Hermansky-Pudlak Syndrome Type-1

LM, Caro-Rivera; S, Malavez-Cajigas; M, Lacourt-Ventura; AP, Rivera-Torres; DE, Marcano-Jiménez; P, López-Colon; J, Muñiz-Hernández; E, Rivera-Jiménez; M, Egozcue-Dionisi; R, Román-Carlo; W, De Jesús-Rojas; MJ, Ramos-Benítez

Age-related neutrophil activation in Hermansky-Pudlak Syndrome Type-1

In: Orphanet J Rare Dis, 2025.

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 Ergosterol Peroxide Disrupts Triple-Negative Breast Cancer Mitochondrial Function and Inhibits Tumor Growth and Metastasis

AL, Bocachica-Adorno; AY, Aponte-Ramos; PS, Rivera-Fuentes; NP, Espinosa-Ponce; LV, Arroyo-Cruz; amd Pérez-Ríos N, Ling T; S, Rivas-Tumanyan; IA, Almodóvar-Rivera; C, Barreto-Gamarra; M, Domenech-García; F, Rivas; MM, Martínez-Montemayor

Ergosterol Peroxide Disrupts Triple-Negative Breast Cancer Mitochondrial Function and Inhibits Tumor Growth and Metastasis

In: Int J Mol Sci, 2025.

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Upregulation of MMP3 Promotes Cisplatin Resistance in Ovarian Cancer

M, Rivera-Serrano; M, Flores-Colón; F, Valiyeva; LM, Meléndez; PE, Vivas-Mejía

Upregulation of MMP3 Promotes Cisplatin Resistance in Ovarian Cancer

In: Int J Mol Sci, 2025.

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Functionalized screen-printed electrodes for non-invasive detection of vascular-endothelial cadherin in extracellular vesicles

W, Meza-Morales; S, Ayus-Martinez; J, Jimenez-Osorio; M, Buendia-Otero; L, López; D, Suleiman; E, Suarez; DO, Freytes; L, Cunci; C, Mora

Functionalized screen-printed electrodes for non-invasive detection of vascular-endothelial cadherin in extracellular vesicles

In: RSC Adv, 2025.

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Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

JG, Medina-Feliciano; G, Valentín-Tirado; K, Luna-Martínez; A, Beltran-Rivera; Y, Miranda-Negrón; JE, Garcia-Arraras

Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

In: Elife, 2025.

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ViBEx: A Visualization Tool for Gene Expression Analysis

Terrefortes-Rosado, M. H.; Nieves-Rivera, A. V.; Ortiz-Zuazaga, H.; Lluberes-Contreras, M

ViBEx: A Visualization Tool for Gene Expression Analysis

In: BioMedInformatics, 2025.

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A Pilot Study of Primary Ciliary Dyskinesia: Sleep-Related Disorders and Neuropsychiatric Comorbidities

RA, Cardona-Quiñones; E, Ramírez-Rivera; E, Álvarez-Torres; SA, Salem-Hernández; NJ, Vargas-Pérez; W, De Jesús-Rojas

A Pilot Study of Primary Ciliary Dyskinesia: Sleep-Related Disorders and Neuropsychiatric Comorbidities

In: J Clin Med, 2025.

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Calcium Sulfide Nanoclusters Trigger DNA Damage and Induce Cell Cycle Arrest in Non-Small-Cell Lung Adenocarcinoma Cells

MM, Figueroa Rosado; K, Muñoz Forti; P, Rodríguez-Rodríguez; G, Arroyo-Martínez; VJ, Rodríguez-Irizarry; A, Ruiz-Rivera; JI, Quinones-Rodriguez; PG, Santiago-Cardona; OM, Rodriguez Martinez; S, Almodovar; ME, Castro; E, Suárez Martínez

Calcium Sulfide Nanoclusters Trigger DNA Damage and Induce Cell Cycle Arrest in Non-Small-Cell Lung Adenocarcinoma Cells

In: Int J Mol Sci, 2025.

Links

Cardiovascular Disease-Associated Non-Coding Variants Disrupt GATA4-DNA Binding and Regulatory Functions

EG, Peña-Martínez; JL, Messon-Bird; JM, Rodríguez-Ríos; R, Velázquez-Roig; DA, Pomales-Matos; A, Rivera-Madera; L, Sanabria-Alberto; AC, Barreiro-Rosario; JA, Figueroa-Rosado; J, Rivera-Del Valle; NE, Muñoz-Páez; EA, Peterson-Peguero; JA, Rodríguez-Martínez

Cardiovascular Disease-Associated Non-Coding Variants Disrupt GATA4-DNA Binding and Regulatory Functions

In: HGG Adv, 2025.

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Oral Microbial Dysbiosis Associated with Alzheimer’s Dementia in Puerto Ricans: A Preliminary Report

Herrero‐Rivera CA Morales H, Soler‐Llompart CM

Oral Microbial Dysbiosis Associated with Alzheimer’s Dementia in Puerto Ricans: A Preliminary Report

In: Alzheimers Dement, 2025.

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Role of the Gut Microbiome in Cognitive Health of Puerto Ricans: A Novel Perspective for Understanding Alzheimer’s Disease

Herrero-Rivera, C. A.; Morales, H.; Soler-Llompart, C. M.; Sala-Morales, A. C.; Olivieri-Henry, G.; Godoy-Vitorino, F.; Sepulveda, V.

Role of the Gut Microbiome in Cognitive Health of Puerto Ricans: A Novel Perspective for Understanding Alzheimer’s Disease

In: Alzheimer's Dement, 2025.

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Characterization of the gut microbiome of Puerto Ricans with Alzheimer’s disease based on their Apolipoprotein E genotype

Olivieri-Henry, G.; Sepulveda, V.; Herrero-Rivera, C. A.; Soler-Llompart, C. M.; Ruiz-Adames, J. A.; M and Santiago-Berríos, Sala-Morales; Morales, H.; Godoy-Vitorino, F

Characterization of the gut microbiome of Puerto Ricans with Alzheimer’s disease based on their Apolipoprotein E genotype

In: Alzheimer's Dement, 2025.

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Solutions to expand microbiome sciences in the Caribbean Region: an insider's perspective

F, Godoy-Vitorino

Solutions to expand microbiome sciences in the Caribbean Region: an insider's perspective

In: Trends Microbiol, 2025.

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 Astrocytic HIV-1 Nef Expression Decreases Glutamate Transporter Expression in the Nucleus Accumbens and Increases Cocaine-Seeking Behavior in Rats

J, Pla-Tenorio; B, Velazquez-Perez; Y, Mendez-Borrero; ML, Cruz; MT, Sepulveda-Orengo; Jr., Noel RJ

Astrocytic HIV-1 Nef Expression Decreases Glutamate Transporter Expression in the Nucleus Accumbens and Increases Cocaine-Seeking Behavior in Rats

In: Pharmaceuticals (Basel), 2025.

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2024

 Effects of temperature and size class on the gut digesta microbiota of the sea urchin Tripneustes ventricosus

R, Rodríguez-Barreras; EL, Tosado-Rodríguez; A, Dominicci-Maura; F, Godoy-Vitorino

Effects of temperature and size class on the gut digesta microbiota of the sea urchin Tripneustes ventricosus

In: PeerJ, 2024.

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Threshold of defensive response in Apis mellifera (honey bees) and subsequent brain gene expression in reaction to noxious stimuli

JP, Acevedo-Gonzalez; A, Galindo-Cardona; NL, Fuenzalida-Uribe; Y, Ortiz-Alvarado; A, Ghezzi; T, Giray

Threshold of defensive response in Apis mellifera (honey bees) and subsequent brain gene expression in reaction to noxious stimuli

In: Entomologia Experimentalis et Applicata, 2024.

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Neuroprotection and activation of anti-inflammatory and plasticity mechanisms by PLC-β inhibition after cholinergic hyperstimulation in hippocampal slices and microglial cells

Pérez-Caraballo, Daraishka

Neuroprotection and activation of anti-inflammatory and plasticity mechanisms by PLC-β inhibition after cholinergic hyperstimulation in hippocampal slices and microglial cells

In: IBRO Neuroscience Reports, 2024.

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Astrocytic HIV-1 Nef expression decreases glutamate transporter expression in the nucleus accumbens and increases cocaine-seeking behavior in rats

J, Pla-Tenorio; B, Velazquez-Perez; Y, Mendez-Borrero; M, Cruz-Rentas; M, Sepulveda-Orengo; Jr, Noel RJ

Astrocytic HIV-1 Nef expression decreases glutamate transporter expression in the nucleus accumbens and increases cocaine-seeking behavior in rats

In: bioRxiv [Preprint], 2024.

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Deferasirox's Anti-Chemoresistance and Anti-Metastatic Effect on Non-Small Cell Lung Carcinoma

Y, Delgado; A, Torres-Sanchez; D, Perez; G, Torres; S, Estrada; N, Ortiz Alvelo; J, Vega; L, Santos; A, Torres; BA, Madera; Y, Ferrer-Acosta

Deferasirox's Anti-Chemoresistance and Anti-Metastatic Effect on Non-Small Cell Lung Carcinoma

In: Biomedicines, 2024.

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Sex-specific effects of chronic stress prior to cocaine exposure on cue- vs drug-induced relapse after prolonged abstinence

RJ, Morales-Silva; Y, Perez-Perez; J, Alvarado-Torres; N, Rivera-Aviles; G, Rodriguez-Torres; U, Gelpi-Dominguez; B, Dominguez-Padovani; A, Amador-Maldonado; MT, Sepulveda-Orengo

Sex-specific effects of chronic stress prior to cocaine exposure on cue- vs drug-induced relapse after prolonged abstinence

In: Behav Brain Res, 2024.

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HL-60 cells as a valuable model to study LPS-induced neutrophil extracellular traps release

SJ, Malavez-Cajigas; FI, Marini-Martinez; M, Lacourt-Ventura; KJ, Rosario-Pacheco; NM, Ortiz-Perez; B, Velazquez-Perez; W, De Jesús-Rojas; DS, Chertow; JR, Strich; MJ, Ramos-Benítez

HL-60 cells as a valuable model to study LPS-induced neutrophil extracellular traps release

In: Heliyon, 2024.

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 Analysis of Sigma-1 Receptor Antagonist BD1047 Effect on Upregulating Proteins in HIV-1-Infected Macrophages Exposed to Cocaine Using Quantitative Proteomics

O, Vélez-López; K, Carrasquillo-Carrión; YM, Cantres-Rosario; E, Machín-Martínez; ME, Álvarez-Ríos; A, Roche-Lima; EL, Tosado-Rodríguez; LM, Meléndez

Analysis of Sigma-1 Receptor Antagonist BD1047 Effect on Upregulating Proteins in HIV-1-Infected Macrophages Exposed to Cocaine Using Quantitative Proteomics

In: Biiomedicines, 2024.

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Evaluation of Open-Source Ciliary Analysis Software in Primary Ciliary Dyskinesia: A Comparative Assessment

ZJ, Demetriou; J, Muñiz-Hernández; G, Rosario-Ortiz; FM, Quiñones; G, Gonzalez-Diaz; MJ, Ramos-Benitez; RA, Mosquera; W, De Jesús-Rojas

Evaluation of Open-Source Ciliary Analysis Software in Primary Ciliary Dyskinesia: A Comparative Assessment

In: Diagnostics (Basel, 2024.

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Insights into Gut Dysbiosis: Inflammatory Diseases, Obesity, and Restoration Approaches

A, Acevedo-Román; N, Pagán-Zayas; LI, Velázquez-Rivera; AC, Torres-Ventura; F, Godoy-Vitorino

Insights into Gut Dysbiosis: Inflammatory Diseases, Obesity, and Restoration Approaches

In: Int J Mol Sci, 2024.

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Novel inhibition of central carbon metabolism pathways by Rac and Cdc42 inhibitor MBQ-167 and paclitaxel

AM, Cruz-Collazo; O, Katsara; N, Grafals-Ruiz; J, Colon Gonzalez; S, Dorta-Estremera; VP, Carlo; N, Chorna; RJ, Schneider; S, Dharmawardhane

Novel inhibition of central carbon metabolism pathways by Rac and Cdc42 inhibitor MBQ-167 and paclitaxel

In: Mol Cancer Ther, 2024.

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Shifts in the gut microbiota of sea urchin Diadema antillarumassociated with the 2022 disease outbreak

Shifts in the gut microbiota of sea urchin Diadema antillarumassociated with the 2022 disease outbreak

In: Front Microbiology, 2024.

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Synthesis of the Novel N-(2-Hexadecynoyl)-l-Homoserine Lactone and Evaluation of Its Antiquorum Sensing Activity in Chromobacterium violaceum

DJ, Sanabria-Ríos; R, García-Del-Valle; S, Bosh-Fonseca; J, González-Pagán; A, Díaz-Rosa; K, Acevedo-Rosario; L, Reyes-Vicente; A, Colom; NM, Carballeira

Synthesis of the Novel N-(2-Hexadecynoyl)-l-Homoserine Lactone and Evaluation of Its Antiquorum Sensing Activity in Chromobacterium violaceum

In: ACS Omega, 2024.

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Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

JG, Medina-Feliciano; G, Valentín-Tirado; K, Luna-Martínez; Y, Miranda-Negrón; JE, García-Arrarás

Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

In: bioRxiv, 2024.

Links

 After an initial Hermansky-Pudlak syndrome clinical diagnosis, molecular testing reveals variants for oculocutaneous albinism type 1B: A case report

J, Serrano-González; I, Montes-Rodríguez; JY, Renta; R, Rojas; CL, Cadilla

After an initial Hermansky-Pudlak syndrome clinical diagnosis, molecular testing reveals variants for oculocutaneous albinism type 1B: A case report

In: Mol Genet Genomic Med, 2024.

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 Immune and Microbial Signatures Associated with PD-1 Blockade Sensitivity in a Preclinical Model for HPV+ Oropharyngeal Cancer

J, Díaz-Rivera; MA, Rodríguez-Rivera; NM, Meléndez-Vázquez; F, Godoy-Vitorino; SM, Dorta-Estremera

Immune and Microbial Signatures Associated with PD-1 Blockade Sensitivity in a Preclinical Model for HPV+ Oropharyngeal Cancer

In: Cancers (Basel), 2024.

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Unraveling the Impact of Six Pentacyclic Triterpenes Regulating Metabolic Pathways on Lung Carcinoma Cells

A, Torres-Sanchez; G, Torres; S, Estrada; D, Perez; C, Garcia; M, Milian; E, Velazquez; V, Molina; Y, Delgado

Unraveling the Impact of Six Pentacyclic Triterpenes Regulating Metabolic Pathways on Lung Carcinoma Cells

In: Pharmaceuticals (Basel), 2024.

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Development of a Neuropeptide Y-Sensitive Implantable Microelectrode for Continuous Measurements

L, Fernández-Vega; Meléndez-Rodríguez D and, Ospina-Alejandro M; K, Casanova; Y, Vázquez; L, Cunci

Development of a Neuropeptide Y-Sensitive Implantable Microelectrode for Continuous Measurements

In: ACS Sens., 2024.

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Plasma Proteins Associated with COVID-19 Severity in Puerto Rico

LJ, Rosario-Rodríguez; YM, Cantres-Rosario; K, Carrasquillo-Carrión; A, Rosa-Díaz; AE, Rodríguez-De Jesús; V, Rivera-Nieves; EL, Tosado-Rodríguez; LB, Méndez; A, Roche-Lima; J, Bertrán; LM, Meléndez

Plasma Proteins Associated with COVID-19 Severity in Puerto Rico

In: Int J Mol Sci, 2024.

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 Extracts Induce INFγ-Independent Activation of CIITA, MHCII, and Increases Inflammation in Human Bronchial Epithelium

H, Jirau-Colón; BD, Jiménez-Vélez

Extracts Induce INFγ-Independent Activation of CIITA, MHCII, and Increases Inflammation in Human Bronchial Epithelium

In: Toxics, 2024.

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New Regulatory roles for Human Serum Amyloid A

CG, García-Cortés; E, Parés-Matos

New Regulatory roles for Human Serum Amyloid A

In: 2024.

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139 entries « 1 of 3 »