Molecular Medicine / Genomics Publications

2023

The Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancer

Crespo GV, Ortiz J; EH, O'Farrill; CP, Vlaar; M, Inyushin; Y, Kucheryavykh; L, Kucheryavykh

The Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancer

2023.

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Gut microbiota variation of a tropical oil-collecting bee species far exceeds that of the honeybee

Kardas E,; AM, González-Rosario; T, Giray; JD, Ackerman; F, Godoy-Vitorino

Gut microbiota variation of a tropical oil-collecting bee species far exceeds that of the honeybee

In: Front Microbiol, 2023.

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SARS-CoV-2 Omicron Replacement of Delta as Predominant Variant, Puerto Rico

GA, Santiago; HR, Volkman; B, Flores; GL, González; KN, Charriez; LC, Huertas; SM, Van Belleghem; V, Rivera-Amill; C, Major; C, Colon; R, Tosado; LE, Adams; M, Marzán; L, Hernández; I, Cardona; E, O'Neill; G, Paz-Bailey; R, Papa; JL, Muñoz-Jordan

SARS-CoV-2 Omicron Replacement of Delta as Predominant Variant, Puerto Rico

In: Emerg Infect Dis., 2023.

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The Antiviral Compound PSP Inhibits HIV-1 Entry via PKR-Dependent Activation in Monocytic Cells

E, Alvarez-Rivera; M, Rodríguez-Valentín; NM, Boukli

The Antiviral Compound PSP Inhibits HIV-1 Entry via PKR-Dependent Activation in Monocytic Cells

In: Viruses, 2023.

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Metadherin Regulates Inflammatory Breast Cancer Invasion and Metastasis

G, Ortiz-Soto; NS, Babilonia-Díaz; MY, Lacourt-Ventura; DM, Rivera-Rodríguez; JI, Quiñones-Rodríguez; M, Colón-Vargas; I, Almodóvar-Rivera; LE, Ferrer-Torres; IJ, Suárez-Arroyo; MM, Martínez-Montemayor

Metadherin Regulates Inflammatory Breast Cancer Invasion and Metastasis

In: Int J Mol Sci. 2023, 2023.

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2022

Decreased CSTB, RAGE and Axl receptor is associated with Zika infection in the human placenta

G, Borges-Vélez; JA, Arroyo; YM, Cantres-Rosario; de Jesus A, Rodriguez; A, Roche-Lima; L, Rosario-Rodriguez; MS, Correa-Rivas; M, Campos-Rivera; J, Rosado-Philippi; LM, Meléndez

Decreased CSTB, RAGE and Axl receptor is associated with Zika infection in the human placenta

In: Cells 2022, 2022.

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Fabrication of paper-based microfluidic devices using a 3D printer and a commercially-available wax filament

A, Espinosa; J, Diaz; E, Vazquez; L, Acosta; A, Santiago; L, Cunci

Fabrication of paper-based microfluidic devices using a 3D printer and a commercially-available wax filament

In: Talanta Open, 2022.

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The Microbiome and Mental Health Across the Lifespan

F, Dickerson; AH, Dilmore; F, Godoy-Vitorino; TT, Nguyen; M, Paulus; AA, Pinto-Tomas; C, Moya-Roman; I, Zuniga-Chaves; EG, Severance; DV, Jeste

The Microbiome and Mental Health Across the Lifespan

In: Curr Top Behav Neurosci, 2022.

Memantine has a nicotinic neuroprotective pathway in acute hippocampal slices after an NMDA insult

Y, Ferrer-Acosta; S, Rodriguez-Massó; D, Pérez; VA, Eterovic; PA, Ferchmin; AH, Martins

Memantine has a nicotinic neuroprotective pathway in acute hippocampal slices after an NMDA insult

In: Toxicol In Vitro. 2022, 2022.

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SCAMP3 Regulates EGFR and Promotes Proliferation and Migration of Triple-Negative Breast Cancer Cells through the Modulation of AKT, ERK, and STAT3 Signaling Pathways

A, Acevedo-Díaz; BM, Morales-Cabán; A, Zayas-Santiago; MM, Martínez-Montemayor; IJ, Suárez-Arroyo

SCAMP3 Regulates EGFR and Promotes Proliferation and Migration of Triple-Negative Breast Cancer Cells through the Modulation of AKT, ERK, and STAT3 Signaling Pathways

2022.

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(2022) Case Report: Unilateral Double Subscapular Artery: A Case Report

Quiñones-Rodríguez, Jailenne I.; Lozada-Miranda, Valeria; Natalia del Mazo-Arbona,; Rosario, Martin (Ed.)

(2022) Case Report: Unilateral Double Subscapular Artery: A Case Report

In: Journal of Clinical and Diagnostic Research, vol. Vol-16(4): AD01-AD03, iss. 2022 Apr, 2022.

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Test Strip Platform Spin-Off for Telomerase Activity Detection: Development of an Electrochemical Biosensor

R, Díaz-Ayala; M, López-Nieves; ES, Colón Berlingeri; CR, Cabrera; L, Cunci; CI, González; PF, Escobar

Test Strip Platform Spin-Off for Telomerase Activity Detection: Development of an Electrochemical Biosensor

In: ACS Omega, iss. 2022 Mar 9, no. 7(11):9964-9972, 2022.

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 Hurricane María drives increased indoor proliferation of filamentous fungi in San Juan, Puerto Rico: a two-year culture-based approach

LN, Vélez-Torres; B, Bolaños-Rosero; F, Godoy-Vitorino; FE, Rivera-Mariani; JP, Maestre; K, Kinney; H, Cavallin

Hurricane María drives increased indoor proliferation of filamentous fungi in San Juan, Puerto Rico: a two-year culture-based approach

In: PeerJ, iss. 2022 Mar 3, no. 10:e12730, 2022.

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Mycobiome-Host Coevolution? The Mycobiome of Ancestral Human Populations Seems to Be Different and Less Diverse Than Those of Extant Native and Urban-Industrialized Populations

J, Reynoso-García; Y, Narganes-Storde; TM, Santiago-Rodriguez; GA, Toranzos

Mycobiome-Host Coevolution? The Mycobiome of Ancestral Human Populations Seems to Be Different and Less Diverse Than Those of Extant Native and Urban-Industrialized Populations

In: Microorganisms, iss. 2022 Feb 16, no. 10(2):459, 2022.

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 Inhibition of Cathepsin B and SAPC Secreted by HIV-Infected Macrophages Reverses Common and Unique Apoptosis Pathways

CN, Zenón-Meléndez; K, Carrasquillo Carrión; Y, Cantres Rosario; A, Roche Lima; LM, Meléndez

Inhibition of Cathepsin B and SAPC Secreted by HIV-Infected Macrophages Reverses Common and Unique Apoptosis Pathways

In: J Proteome Res, iss. 2022 Feb 4, no. 21(2):301-312, 2022.

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Effects of Ferroptosis on the Metabolome in Cardiac Cells: The Role of Glutaminolysis

KM, Rodríguez-Graciani; XR, Chapa-Dubocq; EJ, Ayala-Arroyo; I, Chaves-Negrón; S, Jang; N, Chorna; T, S Maskrey; P, Wipf; S, Javadov

Effects of Ferroptosis on the Metabolome in Cardiac Cells: The Role of Glutaminolysis

In: Antioxidants (Basel), iss. 2022 Jan 29, no. 11(2):278, 2022.

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Voluntary Wheel Running Reduces Vesicle Development in an Endometriosis Animal Model through Modulation of Immune Parameters

Appleyard, Caroline B

Voluntary Wheel Running Reduces Vesicle Development in an Endometriosis Animal Model through Modulation of Immune Parameters

In: Frontiers in Reproductive Health, vol. 3, 2022.

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Cannabinoid receptor type 2 agonist JWH-133 decreases cathepsin B secretion and neurotoxicity from HIV-infected macrophages

LJ, Rosario-Rodríguez; Y, Gerena; LA, García-Requena; LJ, Cartagena-Isern; JC, Cuadrado-Ruiz; G, Borges-Vélez; LM, Meléndez

Cannabinoid receptor type 2 agonist JWH-133 decreases cathepsin B secretion and neurotoxicity from HIV-infected macrophages

In: Sci Rep., iss. 2022 Jan 7, no. 12(1):233, 2022.

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Reduced RBPMS Levels Promote Cell Proliferation and Decrease Cisplatin Sensitivity in Ovarian Cancer Cells

RJ, Rabelo-Fernández; GS, Santiago-Sánchez; RK, Sharma; A, Roche-Lima; KC, Carrion; RAN, Rivera; BI, Quiñones-Díaz; S, Rajasekaran; J, Siddiqui; W, Miles; YS, Rivera; F, Valiyeva; PE, Vivas-Mejia

Reduced RBPMS Levels Promote Cell Proliferation and Decrease Cisplatin Sensitivity in Ovarian Cancer Cells

In: Int J Mol Sci, iss. 2022 Jan 4, no. 23(1):535, 2022.

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The Bacterial and Fungal Gut Microbiota of the Greater Wax Moth, Galleria mellonella L. Consuming Polyethylene and Polystyrene

JM, Ruiz Barrionuevo; B, Vilanova-Cuevas; A, Alvarez; E, Martín; A, Malizia; A, Galindo-Cardona; de Cristóbal RE,; MA, Occhionero; A, Chalup; AC, Monmany-Garzia; F, Godoy-Vitorino

The Bacterial and Fungal Gut Microbiota of the Greater Wax Moth, Galleria mellonella L. Consuming Polyethylene and Polystyrene

In: Front. Microbiol, vol. 13:918861, 2022.

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Oral microbiota and periodontitis severity among Hispanic adults

AP, Ortiz; KT, Acosta-Pagan; C, Oramas-Sepulveda; MA, Castañeda-Avila; B, Vilanova-Cuevas; JM, Ramos-Cartagena; Vivaldi JA, Perez-Santiago J; CM, Perez; F, Godoy-Vitorino

Oral microbiota and periodontitis severity among Hispanic adults

2022.

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2021

Efficacy of Rac and Cdc42 Inhibitor MBQ-167 in Triple-negative Breast Cancer

A, Cruz-Collazo; JF, Ruiz-Calderon; H, Picon; LD, Borrero-Garcia; I, Lopez; L, Castillo-Pichardo; M, Del Mar Maldonado; J, Duconge; JI, Medina; MJ, Bayro; E, Hernández-O'Farrill; CP, Vlaar; S., Dharmawardhane

Efficacy of Rac and Cdc42 Inhibitor MBQ-167 in Triple-negative Breast Cancer

In: Mol Cancer Ther., iss. 2021 Dec, no. 20(12):2420-2432, 2021.

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Selection and isolation define a heterogeneous divergence landscape between hybridizing Heliconius butterflies

SM, Van Belleghem; JM, Cole; G, Montejo-Kovacevich; CN, Bacquet; WO, McMillan; R, Papa; BA, Counterman

Selection and isolation define a heterogeneous divergence landscape between hybridizing Heliconius butterflies

In: Evolution, iss. 2021 Sep, no. 75(9):2251-2268, 2021.

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Trophic niches reflect compositional differences in microbiota among Caribbean sea urchins

R, Rodríguez-Barreras; EL, Tosado-Rodríguez; F, Godoy-Vitorino

Trophic niches reflect compositional differences in microbiota among Caribbean sea urchins

In: PeerJ, iss. 2021 Aug 31, no. 9:e12084, 2021.

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 Fluoride binding to characteristic heme-pocket centers: Insights into ligand stability

K, Frankenfield; D, Marchany-Rivera; KG, Flanders; A, Cruz-Balberdy; J, Lopez-Garriga; J, Cerda

Fluoride binding to characteristic heme-pocket centers: Insights into ligand stability

In: J Inorg Biochem, iss. 2021 Nov, no. 224:111578, 2021.

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Soy and Frequent Dairy Consumption with Subsequent Equol Production Reveals Decreased Gut Health in a Cohort of Healthy Puerto Rican Women

MY, Lacourt-Ventura; B, Vilanova-Cuevas; D, Rivera-Rodríguez; R, Rosario-Acevedo; C, Miranda; G, Maldonado-Martínez; J, Maysonet; Vargas D, Ruiz Y; R, Hunter-Mellado; LA, Cubano; S, Dharmawardhane; JW, Lampe; A, Baerga-Ortiz; F, Godoy-Vitorino; MM, Martínez-Montemayor

Soy and Frequent Dairy Consumption with Subsequent Equol Production Reveals Decreased Gut Health in a Cohort of Healthy Puerto Rican Women

In: Int J Environ Res Public Health, iss. 2021 Aug 4, no. 18(16, 2021.

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 Zika virus infection of the placenta alters extracellular matrix proteome

G, Borges-Vélez; J, Rosado-Philippi; YM, Cantres-Rosario; K, Carrasquillo-Carrion; A, Roche-Lima; Pérez-Vargas J, González-Martínez A; MS, Correa-Rivas; LM, Meléndez

Zika virus infection of the placenta alters extracellular matrix proteome

In: J Mol Histol, iss. 2021 Jul 15, 2021.

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Iron Chelator Transmetalative Approach to Inhibit Human Ribonucleotide Reductase

K, Gaur; SC, Pérez Otero; JA, Benjamín-Rivera; I, Rodríguez; SA, Loza-Rosas; AM, Vázquez Salgado; EA, Akam; L, Hernández-Matias; RK, Sharma; N, Alicea; M, Kowaleff; AV, Washington; AV, Astashkin; E, Tomat; AD, Tinoco

Iron Chelator Transmetalative Approach to Inhibit Human Ribonucleotide Reductase

In: JACS, vol. 1(6), no. 865-878, 2021.

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