Molecular Medicine / Genomics Publications

57 entries « 1 of 2 »

2024

Shifts in the gut microbiota of sea urchin Diadema antillarumassociated with the 2022 disease outbreak

Shifts in the gut microbiota of sea urchin Diadema antillarumassociated with the 2022 disease outbreak

In: Front Microbiology, 2024.

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Synthesis of the Novel N-(2-Hexadecynoyl)-l-Homoserine Lactone and Evaluation of Its Antiquorum Sensing Activity in Chromobacterium violaceum

DJ, Sanabria-Ríos; R, García-Del-Valle; S, Bosh-Fonseca; J, González-Pagán; A, Díaz-Rosa; K, Acevedo-Rosario; L, Reyes-Vicente; A, Colom; NM, Carballeira

Synthesis of the Novel N-(2-Hexadecynoyl)-l-Homoserine Lactone and Evaluation of Its Antiquorum Sensing Activity in Chromobacterium violaceum

In: ACS Omega, 2024.

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 After an initial Hermansky-Pudlak syndrome clinical diagnosis, molecular testing reveals variants for oculocutaneous albinism type 1B: A case report

J, Serrano-González; I, Montes-Rodríguez; JY, Renta; R, Rojas; CL, Cadilla

After an initial Hermansky-Pudlak syndrome clinical diagnosis, molecular testing reveals variants for oculocutaneous albinism type 1B: A case report

In: Mol Genet Genomic Med, 2024.

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Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

JG, Medina-Feliciano; G, Valentín-Tirado; K, Luna-Martínez; Y, Miranda-Negrón; JE, García-Arrarás

Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

In: bioRxiv, 2024.

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Unraveling the Impact of Six Pentacyclic Triterpenes Regulating Metabolic Pathways on Lung Carcinoma Cells

A, Torres-Sanchez; G, Torres; S, Estrada; D, Perez; C, Garcia; M, Milian; E, Velazquez; V, Molina; Y, Delgado

Unraveling the Impact of Six Pentacyclic Triterpenes Regulating Metabolic Pathways on Lung Carcinoma Cells

In: Pharmaceuticals (Basel), 2024.

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Plasma Proteins Associated with COVID-19 Severity in Puerto Rico

LJ, Rosario-Rodríguez; YM, Cantres-Rosario; K, Carrasquillo-Carrión; A, Rosa-Díaz; AE, Rodríguez-De Jesús; V, Rivera-Nieves; EL, Tosado-Rodríguez; LB, Méndez; A, Roche-Lima; J, Bertrán; LM, Meléndez

Plasma Proteins Associated with COVID-19 Severity in Puerto Rico

In: Int J Mol Sci, 2024.

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Improved LINE-1 Detection through Pattern Matching by Increasing Probe Length

JO, López; Quiñones J and, Martínez ED

Improved LINE-1 Detection through Pattern Matching by Increasing Probe Length

In: Biology (Basel), 2024.

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 Vaginal Microbiota and HPV in Latin America: A Narrative Review

E, Tosado-Rodríguez; I, Alvarado-Vélez; J, Romaguera; F, Godoy-Vitorino

Vaginal Microbiota and HPV in Latin America: A Narrative Review

In: Microorganisms, 2024.

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Advancing Primary Ciliary Dyskinesia Diagnosis through High-Speed Video Microscopy Analysis

W, De Jesús-Rojas; ZJ, Demetriou; J, Muñiz-Hernández; G, Rosario-Ortiz; FM, Quiñones; MJ, Ramos-Benitez; RA, Mosquera

Advancing Primary Ciliary Dyskinesia Diagnosis through High-Speed Video Microscopy Analysis

In: Cells, 2024.

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Gut microbiota composition is associated with the efficacy of Delta-24-RGDOX in malignant gliomas

NM, Meléndez-Vázquez; TT, Nguyen; X, Fan; AR, López-Rivas; J, Fueyo; C, Gomez-Manzano; F, Godoy-Vitorino

Gut microbiota composition is associated with the efficacy of Delta-24-RGDOX in malignant gliomas

In: Mol Ther Oncol, 2024.

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Estradiol reduction through aromatase inhibition impairs cocaine seeking in male rats

JK, Alvarado-Torres; R, Morales-Silva; de Leon A, Sanabria Ponce; G, Rodriguez-Torres; J, Perez-Torres; Y, Perez-Perez; D, Mueller; MT, Sepulveda-Orengo

Estradiol reduction through aromatase inhibition impairs cocaine seeking in male rats

In: Front Behav Neuroscience, 2024.

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Mechanistics of pH-Dependent Sulfmyoglobin Formation: Spin Control and His64 Proton Relay

Mackenzie, A.; Santos, L.; Arbelo, H.; Wymore, T.; Garriga, J.

Mechanistics of pH-Dependent Sulfmyoglobin Formation: Spin Control and His64 Proton Relay

In: Journal of Chemistry, vol. 2024, 2024.

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2023

In vitro generation of murine myeloid-derived suppressor cells from hematopoietic progenitor cells

LM, Hernandez-Delgado; A, Laboy-Figueroa; A, Lopez-Velazquez; C, Flores-Ortiz; K, Alicea-Torres

In vitro generation of murine myeloid-derived suppressor cells from hematopoietic progenitor cells

In: Methods Cell Biol, 2023.

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Inflammatory cytokines and a diverse cervicovaginal microbiota associate with cervical dysplasia in a cohort of Hispanics living in Puerto Rico

E, Tosado-Rodríguez; LB, Mendez; AM, Espino; S, Dorta-Estremera; EE, Aquino; J, Romaguera; F, Godoy-Vitorino

Inflammatory cytokines and a diverse cervicovaginal microbiota associate with cervical dysplasia in a cohort of Hispanics living in Puerto Rico

In: 2023.

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Determining the Safety of the Tobacco Cembranoid (1S,2E,4R,6R,7E,11E)-Cembratriene-4,6-diol (4R): A Translational Study in Nonhuman Primates

N, Sabeva; W, Castro; Y, Ferrer-Acosta; P.A, Ferchmin; V.A, Eterovic; D, Sierra-Mercado; N, Pérez-Rios; S, Rivas-Tumanyan; A.H, Martins

Determining the Safety of the Tobacco Cembranoid (1S,2E,4R,6R,7E,11E)-Cembratriene-4,6-diol (4R): A Translational Study in Nonhuman Primates

In: 2023.

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Evolutionary dynamics of genome size and content during the adaptive radiation of Heliconiini butterflies

F, Cicconardi; E, Milanetti; de Castro EC, Pinheiro; A, Mazo-Vargas; SM, Van Belleghem; AA, Ruggieri; P, Rastas; J, Hanly; E, Evans; CD, Jiggins; W, Owen McMillan; R, Papa; D, Di Marino; A, Martin; SH, Montgomery

Evolutionary dynamics of genome size and content during the adaptive radiation of Heliconiini butterflies

In: Nat Commun, 2023.

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The Characterization and Evaluation of the Soluble Triggering Receptor Expressed on Myeloid Cells-like Transcript-1 in Stable Coronary Artery Disease

Z, Bayrón-Marrero; S, Branfield; J, Menéndez-Pérez; Nieves-López B, Ospina L; Y, Cantres-Rosario; LM, Melendez; R, Hunter; A, Gibson; G, Maldonado-Martínez; AV, Washington

The Characterization and Evaluation of the Soluble Triggering Receptor Expressed on Myeloid Cells-like Transcript-1 in Stable Coronary Artery Disease

In: Int J Mol Sci., 2023.

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The cervical microbiota of Hispanics living in Puerto Rico is nonoptimal regardless of HPV status

D, Vargas-Robles; J, Romaguera; I, Alvarado-Velez; E, Tosado-Rodríguez; A, Dominicci-Maura; M, Sanchez; KJ, Wiggin; M, Martinez-Ferrer; JA, Gilbert; LJ, Forney; F, Godoy-Vitorino

The cervical microbiota of Hispanics living in Puerto Rico is nonoptimal regardless of HPV status

In: mSystems, 2023.

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Mechanisms of Regulation of the CHRDL1 Gene by the TWIST2 and ADD1/SREBP1c Transcription Factors

JJ, Casasnovas-Nieves; Y, Rodríguez; HL, Franco; CL, Cadilla

Mechanisms of Regulation of the CHRDL1 Gene by the TWIST2 and ADD1/SREBP1c Transcription Factors

In: Genes (Basel), 2023.

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Substrate topographies modulate the secretory activity of human bone marrow mesenchymal stem cells

H, Rosado-Galindo; M, Domenech

Substrate topographies modulate the secretory activity of human bone marrow mesenchymal stem cells

In: Stem Cell Res Ther, 2023.

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Assessment of Vibrio populations in a transect of Rhizophora mangle in Punta Galeta, Panamá: culture-dependent analyses reveal biotechnological applications

J, Sánchez-Gallego; L, Atencio; J, Pérez; O, Dupuy; E, Díaz-Ferguson; F, Godoy-Vitorino

Assessment of Vibrio populations in a transect of Rhizophora mangle in Punta Galeta, Panamá: culture-dependent analyses reveal biotechnological applications

In: Rev Biol Trop, 2023.

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Oncogenic Proteomics Approaches for Translational Research and HIV-Associated Malignancy Mechanisms

E, Alvarez-Rivera; EJ, Ortiz-Hernández; E, Lugo; LM, Lozada-Reyes; NM, Boukli

Oncogenic Proteomics Approaches for Translational Research and HIV-Associated Malignancy Mechanisms

In: Proteomes, 2023.

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Rac and Cdc42 inhibitors reduce macrophage function in breast cancer preclinical models

A, Torres-Sanchez; M, Rivera-Robles; L, Castillo-Pichardo; M, Martínez-Ferrer; SM, Dorta-Estremera; S, Dharmawardhane

Rac and Cdc42 inhibitors reduce macrophage function in breast cancer preclinical models

In: Front Oncol., 2023.

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The Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancer

Crespo GV, Ortiz J; EH, O'Farrill; CP, Vlaar; M, Inyushin; Y, Kucheryavykh; L, Kucheryavykh

The Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancer

2023.

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Gut microbiota variation of a tropical oil-collecting bee species far exceeds that of the honeybee

Kardas E,; AM, González-Rosario; T, Giray; JD, Ackerman; F, Godoy-Vitorino

Gut microbiota variation of a tropical oil-collecting bee species far exceeds that of the honeybee

In: Front Microbiol, 2023.

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SARS-CoV-2 Omicron Replacement of Delta as Predominant Variant, Puerto Rico

GA, Santiago; HR, Volkman; B, Flores; GL, González; KN, Charriez; LC, Huertas; SM, Van Belleghem; V, Rivera-Amill; C, Major; C, Colon; R, Tosado; LE, Adams; M, Marzán; L, Hernández; I, Cardona; E, O'Neill; G, Paz-Bailey; R, Papa; JL, Muñoz-Jordan

SARS-CoV-2 Omicron Replacement of Delta as Predominant Variant, Puerto Rico

In: Emerg Infect Dis., 2023.

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The Antiviral Compound PSP Inhibits HIV-1 Entry via PKR-Dependent Activation in Monocytic Cells

E, Alvarez-Rivera; M, Rodríguez-Valentín; NM, Boukli

The Antiviral Compound PSP Inhibits HIV-1 Entry via PKR-Dependent Activation in Monocytic Cells

In: Viruses, 2023.

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High level of novelty under the hood of convergent evolution

SM, Van Belleghem; AA, Ruggieri; C, Concha; L, Livraghi; L, Hebberecht; ES, Rivera; JG, Ogilvie; JJ, Hanly; IA, Warren; S, Planas; Y, Ortiz-Ruiz; R, Reed; JJ, Lewis; CD, Jiggins; BA, Counterman; WO, McMillan; R, Papa

High level of novelty under the hood of convergent evolution

In: 2023.

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Surface roughness modulates EGFR signaling and stemness of triple-negative breast cancer cells

H, Rosado-Galindo; M, Domenech

Surface roughness modulates EGFR signaling and stemness of triple-negative breast cancer cells

In: Front Cell Dev Biol, 2023.

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Metadherin Regulates Inflammatory Breast Cancer Invasion and Metastasis

G, Ortiz-Soto; NS, Babilonia-Díaz; MY, Lacourt-Ventura; DM, Rivera-Rodríguez; JI, Quiñones-Rodríguez; M, Colón-Vargas; I, Almodóvar-Rivera; LE, Ferrer-Torres; IJ, Suárez-Arroyo; MM, Martínez-Montemayor

Metadherin Regulates Inflammatory Breast Cancer Invasion and Metastasis

In: Int J Mol Sci. 2023, 2023.

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Insights into Sulfhemoglobin Detection: UV-Vis and Fluorescence Spectroscopy Correlations

L., Santos Velazquez; J., Garriga-Lopez

Insights into Sulfhemoglobin Detection: UV-Vis and Fluorescence Spectroscopy Correlations

In: Journal of Chemistry, vol. 2023, 2023.

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2022

Decreased CSTB, RAGE and Axl receptor is associated with Zika infection in the human placenta

G, Borges-Vélez; JA, Arroyo; YM, Cantres-Rosario; de Jesus A, Rodriguez; A, Roche-Lima; L, Rosario-Rodriguez; MS, Correa-Rivas; M, Campos-Rivera; J, Rosado-Philippi; LM, Meléndez

Decreased CSTB, RAGE and Axl receptor is associated with Zika infection in the human placenta

In: Cells 2022, 2022.

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 Genome-wide species delimitation analyses of a silverside fish species complex in central Mexico indicate taxonomic over-splitting

VJ, Piñeros; C, Del R Pedraza-Marrón; I, Betancourt-Resendes; N, Calderón-Cortés; R, Betancur-R; O, Domínguez-Domínguez

Genome-wide species delimitation analyses of a silverside fish species complex in central Mexico indicate taxonomic over-splitting

In: 2022.

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Fabrication of paper-based microfluidic devices using a 3D printer and a commercially-available wax filament

A, Espinosa; J, Diaz; E, Vazquez; L, Acosta; A, Santiago; L, Cunci

Fabrication of paper-based microfluidic devices using a 3D printer and a commercially-available wax filament

In: Talanta Open, 2022.

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The Microbiome and Mental Health Across the Lifespan

F, Dickerson; AH, Dilmore; F, Godoy-Vitorino; TT, Nguyen; M, Paulus; AA, Pinto-Tomas; C, Moya-Roman; I, Zuniga-Chaves; EG, Severance; DV, Jeste

The Microbiome and Mental Health Across the Lifespan

In: Curr Top Behav Neurosci, 2022.

Memantine has a nicotinic neuroprotective pathway in acute hippocampal slices after an NMDA insult

Y, Ferrer-Acosta; S, Rodriguez-Massó; D, Pérez; VA, Eterovic; PA, Ferchmin; AH, Martins

Memantine has a nicotinic neuroprotective pathway in acute hippocampal slices after an NMDA insult

In: Toxicol In Vitro. 2022, 2022.

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SCAMP3 Regulates EGFR and Promotes Proliferation and Migration of Triple-Negative Breast Cancer Cells through the Modulation of AKT, ERK, and STAT3 Signaling Pathways

A, Acevedo-Díaz; BM, Morales-Cabán; A, Zayas-Santiago; MM, Martínez-Montemayor; IJ, Suárez-Arroyo

SCAMP3 Regulates EGFR and Promotes Proliferation and Migration of Triple-Negative Breast Cancer Cells through the Modulation of AKT, ERK, and STAT3 Signaling Pathways

2022.

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(2022) Case Report: Unilateral Double Subscapular Artery: A Case Report

Quiñones-Rodríguez, Jailenne I.; Lozada-Miranda, Valeria; Natalia del Mazo-Arbona,; Rosario, Martin (Ed.)

(2022) Case Report: Unilateral Double Subscapular Artery: A Case Report

In: Journal of Clinical and Diagnostic Research, vol. Vol-16(4): AD01-AD03, iss. 2022 Apr, 2022.

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Metagenomic clustering reveals microbial contamination as an essential consideration in ultraconserved element design for phylogenomics with insect museum specimens

AR, Van Dam; JO, Covas Orizondo; AW, Lam; DD, McKenna; MH, Van Dam

Metagenomic clustering reveals microbial contamination as an essential consideration in ultraconserved element design for phylogenomics with insect museum specimens

In: Ecol. Evol., 2022.

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Test Strip Platform Spin-Off for Telomerase Activity Detection: Development of an Electrochemical Biosensor

R, Díaz-Ayala; M, López-Nieves; ES, Colón Berlingeri; CR, Cabrera; L, Cunci; CI, González; PF, Escobar

Test Strip Platform Spin-Off for Telomerase Activity Detection: Development of an Electrochemical Biosensor

In: ACS Omega, iss. 2022 Mar 9, no. 7(11):9964-9972, 2022.

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 Hurricane María drives increased indoor proliferation of filamentous fungi in San Juan, Puerto Rico: a two-year culture-based approach

LN, Vélez-Torres; B, Bolaños-Rosero; F, Godoy-Vitorino; FE, Rivera-Mariani; JP, Maestre; K, Kinney; H, Cavallin

Hurricane María drives increased indoor proliferation of filamentous fungi in San Juan, Puerto Rico: a two-year culture-based approach

In: PeerJ, iss. 2022 Mar 3, no. 10:e12730, 2022.

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Mycobiome-Host Coevolution? The Mycobiome of Ancestral Human Populations Seems to Be Different and Less Diverse Than Those of Extant Native and Urban-Industrialized Populations

J, Reynoso-García; Y, Narganes-Storde; TM, Santiago-Rodriguez; GA, Toranzos

Mycobiome-Host Coevolution? The Mycobiome of Ancestral Human Populations Seems to Be Different and Less Diverse Than Those of Extant Native and Urban-Industrialized Populations

In: Microorganisms, iss. 2022 Feb 16, no. 10(2):459, 2022.

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 Inhibition of Cathepsin B and SAPC Secreted by HIV-Infected Macrophages Reverses Common and Unique Apoptosis Pathways

CN, Zenón-Meléndez; K, Carrasquillo Carrión; Y, Cantres Rosario; A, Roche Lima; LM, Meléndez

Inhibition of Cathepsin B and SAPC Secreted by HIV-Infected Macrophages Reverses Common and Unique Apoptosis Pathways

In: J Proteome Res, iss. 2022 Feb 4, no. 21(2):301-312, 2022.

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Effects of Ferroptosis on the Metabolome in Cardiac Cells: The Role of Glutaminolysis

KM, Rodríguez-Graciani; XR, Chapa-Dubocq; EJ, Ayala-Arroyo; I, Chaves-Negrón; S, Jang; N, Chorna; T, S Maskrey; P, Wipf; S, Javadov

Effects of Ferroptosis on the Metabolome in Cardiac Cells: The Role of Glutaminolysis

In: Antioxidants (Basel), iss. 2022 Jan 29, no. 11(2):278, 2022.

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Voluntary Wheel Running Reduces Vesicle Development in an Endometriosis Animal Model through Modulation of Immune Parameters

Appleyard, Caroline B

Voluntary Wheel Running Reduces Vesicle Development in an Endometriosis Animal Model through Modulation of Immune Parameters

In: Frontiers in Reproductive Health, vol. 3, 2022.

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Cannabinoid receptor type 2 agonist JWH-133 decreases cathepsin B secretion and neurotoxicity from HIV-infected macrophages

LJ, Rosario-Rodríguez; Y, Gerena; LA, García-Requena; LJ, Cartagena-Isern; JC, Cuadrado-Ruiz; G, Borges-Vélez; LM, Meléndez

Cannabinoid receptor type 2 agonist JWH-133 decreases cathepsin B secretion and neurotoxicity from HIV-infected macrophages

In: Sci Rep., iss. 2022 Jan 7, no. 12(1):233, 2022.

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Reduced RBPMS Levels Promote Cell Proliferation and Decrease Cisplatin Sensitivity in Ovarian Cancer Cells

RJ, Rabelo-Fernández; GS, Santiago-Sánchez; RK, Sharma; A, Roche-Lima; KC, Carrion; RAN, Rivera; BI, Quiñones-Díaz; S, Rajasekaran; J, Siddiqui; W, Miles; YS, Rivera; F, Valiyeva; PE, Vivas-Mejia

Reduced RBPMS Levels Promote Cell Proliferation and Decrease Cisplatin Sensitivity in Ovarian Cancer Cells

In: Int J Mol Sci, iss. 2022 Jan 4, no. 23(1):535, 2022.

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Hemoglobin I from Lucina pectinata on Collagen Scaffold: A Prospective Hydrogen Sulfide Scavenger

Vargas, S. J.; Quintana, A; Lopez-Garriga, J

Hemoglobin I from Lucina pectinata on Collagen Scaffold: A Prospective Hydrogen Sulfide Scavenger

In: Journal of Chemistry, 2022.

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Oral microbiota and periodontitis severity among Hispanic adults

AP, Ortiz; KT, Acosta-Pagan; C, Oramas-Sepulveda; MA, Castañeda-Avila; B, Vilanova-Cuevas; JM, Ramos-Cartagena; Vivaldi JA, Perez-Santiago J; CM, Perez; F, Godoy-Vitorino

Oral microbiota and periodontitis severity among Hispanic adults

2022.

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The Bacterial and Fungal Gut Microbiota of the Greater Wax Moth, Galleria mellonella L. Consuming Polyethylene and Polystyrene

JM, Ruiz Barrionuevo; B, Vilanova-Cuevas; A, Alvarez; E, Martín; A, Malizia; A, Galindo-Cardona; de Cristóbal RE,; MA, Occhionero; A, Chalup; AC, Monmany-Garzia; F, Godoy-Vitorino

The Bacterial and Fungal Gut Microbiota of the Greater Wax Moth, Galleria mellonella L. Consuming Polyethylene and Polystyrene

In: Front. Microbiol, vol. 13:918861, 2022.

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