Molecular Medicine / Genomics Publications

81 entries « 1 of 2 »

2025

Clinical Symptom Patterns as Predictors of SARS-CoV-2 Infection in Healthcare Workers in Puerto Rico

Ortiz DV, Romaguera J; JL, Santos Agrait; F, Vázquez; ME, Pérez; CD, Zorrilla; F, Godoy-Vitorino

Clinical Symptom Patterns as Predictors of SARS-CoV-2 Infection in Healthcare Workers in Puerto Rico

In: Int J Environ Res Public Health, 2025.

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WntA expression and wing transcriptomics illuminate the evolution of stripe patterns in skipper butterflies

JD, Alqassar; TS, Rivera-Miranda; JJ, Hanly; CR, Day; SM, Planas Soto-Navarro; PB, Frandsen; Papa R, Martin A

WntA expression and wing transcriptomics illuminate the evolution of stripe patterns in skipper butterflies

In: Biol Open, 2025.

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Molecular and culture-based identification of Aspergillus species in water-impacted homes following Hurricane María in Puerto Rico

LN, Vélez-Torres; B, Bolaños-Rosero; Godoy-Vitorino,; FE, Rivera-Mariani; JP, Maestre; K, Kinney; H, Cavallin-Calanche

Molecular and culture-based identification of Aspergillus species in water-impacted homes following Hurricane María in Puerto Rico

In: Sci Rep, 2025.

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Air Pollutants in Puerto Rico: Key Pollutants and Carcinogenic Properties

D, Kaya; C, Santiago; E, Pernas; S, Truong; G, Martinez; LB, Méndez; Y, Delgado

Air Pollutants in Puerto Rico: Key Pollutants and Carcinogenic Properties

In: Int J Environ Res Public Health, 2025.

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Congenital heart disease missense mutations in the TBX5 DNA-binding domain alter thermal stability and DNA-binding affinity

A, Rivera-Madera; EG, Peña-Martínez; JL, Messon-Bird; DA, Pomales-Matos; OL, Echevarría-Bonilla; L, Sanabria-Alberto; EA, Peterson-Peguero; JA, Rodríguez-Martínez

Congenital heart disease missense mutations in the TBX5 DNA-binding domain alter thermal stability and DNA-binding affinity

In: G3 (Bethesda), 2025.

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The Effect of Cefazolin on the Gut Microbiome of Female Rats After Spinal Cord Injury

LH, Pagán-Rivera; F, Godoy-Vitorino; NM, Meléndez-Vázquez; SE, Ocasio-Rivera; ME, Santiago-Gascot; JM, Santiago; I, Salgado; V, González; O, Martínez-Guzmán; M, Cáceres-Chacón; A, Torrado-Tapias; JD, Miranda

The Effect of Cefazolin on the Gut Microbiome of Female Rats After Spinal Cord Injury

In: Microorganisms, 2025.

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Speaking science in a fractured world: making truth land when facts alone cannot

RM, Calisi-Rodríguez; K, Alicea-Torres; JC, Peng; NA, Theodosiou; CD, Rogers

Speaking science in a fractured world: making truth land when facts alone cannot

In: Development, 2025.

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Connecting Innovation and Trust through Translational Sciences - A Need for a Community Focus and Effective Education Strategies

F, Godoy-Vitorino; M, Borrero; J, Pérez-Santiago; R, García-García; C, Gomez-Manzano

Connecting Innovation and Trust through Translational Sciences - A Need for a Community Focus and Effective Education Strategies

In: Health Sci J, 2025.

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Strengthening Integrative Microbiome Research Through Regional Leadership

F, Godoy-Vitorino

Strengthening Integrative Microbiome Research Through Regional Leadership

In: Int J Environ Res Public Health, 2025.

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RSPH4A-PCDx: An Index to Predict Lung Function Decline in Primary Ciliary Dyskinesia

G, Román-Ríos; G, Rosario-Ortiz; MJ, Ramos-Benitez; RA, Mosquera; W, De Jesús-Rojas

RSPH4A-PCDx: An Index to Predict Lung Function Decline in Primary Ciliary Dyskinesia

In: Adv Respir Med, 2025.

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Determining the role of FAP1 in S. cerevisiae, cultivated in Nitrogen-limited media

MM, Fajardo; EIP, Matos

Determining the role of FAP1 in S. cerevisiae, cultivated in Nitrogen-limited media

In: Int J Mol Biol Open Access, 2025.

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Challenges and Opportunities: Interplay between Infectious Disease and Antimicrobial Resistance in Medical Device Surface Applications

V, Ortiz-Gómez; R, Maldonado-Hernández

Challenges and Opportunities: Interplay between Infectious Disease and Antimicrobial Resistance in Medical Device Surface Applications

In: ACS Omega, 2025.

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 Ergosterol Peroxide Disrupts Triple-Negative Breast Cancer Mitochondrial Function and Inhibits Tumor Growth and Metastasis

AL, Bocachica-Adorno; AY, Aponte-Ramos; PS, Rivera-Fuentes; NP, Espinosa-Ponce; LV, Arroyo-Cruz; amd Pérez-Ríos N, Ling T; S, Rivas-Tumanyan; IA, Almodóvar-Rivera; C, Barreto-Gamarra; M, Domenech-García; F, Rivas; MM, Martínez-Montemayor

Ergosterol Peroxide Disrupts Triple-Negative Breast Cancer Mitochondrial Function and Inhibits Tumor Growth and Metastasis

In: Int J Mol Sci, 2025.

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Upregulation of MMP3 Promotes Cisplatin Resistance in Ovarian Cancer

M, Rivera-Serrano; M, Flores-Colón; F, Valiyeva; LM, Meléndez; PE, Vivas-Mejía

Upregulation of MMP3 Promotes Cisplatin Resistance in Ovarian Cancer

In: Int J Mol Sci, 2025.

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Functionalized screen-printed electrodes for non-invasive detection of vascular-endothelial cadherin in extracellular vesicles

W, Meza-Morales; S, Ayus-Martinez; J, Jimenez-Osorio; M, Buendia-Otero; L, López; D, Suleiman; E, Suarez; DO, Freytes; L, Cunci; C, Mora

Functionalized screen-printed electrodes for non-invasive detection of vascular-endothelial cadherin in extracellular vesicles

In: RSC Adv, 2025.

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Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

JG, Medina-Feliciano; G, Valentín-Tirado; K, Luna-Martínez; A, Beltran-Rivera; Y, Miranda-Negrón; JE, Garcia-Arraras

Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

In: Elife, 2025.

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Calcium Sulfide Nanoclusters Trigger DNA Damage and Induce Cell Cycle Arrest in Non-Small-Cell Lung Adenocarcinoma Cells

MM, Figueroa Rosado; K, Muñoz Forti; P, Rodríguez-Rodríguez; G, Arroyo-Martínez; VJ, Rodríguez-Irizarry; A, Ruiz-Rivera; JI, Quinones-Rodriguez; PG, Santiago-Cardona; OM, Rodriguez Martinez; S, Almodovar; ME, Castro; E, Suárez Martínez

Calcium Sulfide Nanoclusters Trigger DNA Damage and Induce Cell Cycle Arrest in Non-Small-Cell Lung Adenocarcinoma Cells

In: Int J Mol Sci, 2025.

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Cardiovascular Disease-Associated Non-Coding Variants Disrupt GATA4-DNA Binding and Regulatory Functions

EG, Peña-Martínez; JL, Messon-Bird; JM, Rodríguez-Ríos; R, Velázquez-Roig; DA, Pomales-Matos; A, Rivera-Madera; L, Sanabria-Alberto; AC, Barreiro-Rosario; JA, Figueroa-Rosado; J, Rivera-Del Valle; NE, Muñoz-Páez; EA, Peterson-Peguero; JA, Rodríguez-Martínez

Cardiovascular Disease-Associated Non-Coding Variants Disrupt GATA4-DNA Binding and Regulatory Functions

In: HGG Adv, 2025.

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Solutions to expand microbiome sciences in the Caribbean Region: an insider's perspective

F, Godoy-Vitorino

Solutions to expand microbiome sciences in the Caribbean Region: an insider's perspective

In: Trends Microbiol, 2025.

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2024

 Effects of temperature and size class on the gut digesta microbiota of the sea urchin Tripneustes ventricosus

R, Rodríguez-Barreras; EL, Tosado-Rodríguez; A, Dominicci-Maura; F, Godoy-Vitorino

Effects of temperature and size class on the gut digesta microbiota of the sea urchin Tripneustes ventricosus

In: PeerJ, 2024.

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Astrocytic HIV-1 Nef expression decreases glutamate transporter expression in the nucleus accumbens and increases cocaine-seeking behavior in rats

J, Pla-Tenorio; B, Velazquez-Perez; Y, Mendez-Borrero; M, Cruz-Rentas; M, Sepulveda-Orengo; Jr, Noel RJ

Astrocytic HIV-1 Nef expression decreases glutamate transporter expression in the nucleus accumbens and increases cocaine-seeking behavior in rats

In: bioRxiv [Preprint], 2024.

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Evaluation of Open-Source Ciliary Analysis Software in Primary Ciliary Dyskinesia: A Comparative Assessment

ZJ, Demetriou; J, Muñiz-Hernández; G, Rosario-Ortiz; FM, Quiñones; G, Gonzalez-Diaz; MJ, Ramos-Benitez; RA, Mosquera; W, De Jesús-Rojas

Evaluation of Open-Source Ciliary Analysis Software in Primary Ciliary Dyskinesia: A Comparative Assessment

In: Diagnostics (Basel, 2024.

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Insights into Gut Dysbiosis: Inflammatory Diseases, Obesity, and Restoration Approaches

A, Acevedo-Román; N, Pagán-Zayas; LI, Velázquez-Rivera; AC, Torres-Ventura; F, Godoy-Vitorino

Insights into Gut Dysbiosis: Inflammatory Diseases, Obesity, and Restoration Approaches

In: Int J Mol Sci, 2024.

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Shifts in the gut microbiota of sea urchin Diadema antillarumassociated with the 2022 disease outbreak

Shifts in the gut microbiota of sea urchin Diadema antillarumassociated with the 2022 disease outbreak

In: Front Microbiology, 2024.

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Synthesis of the Novel N-(2-Hexadecynoyl)-l-Homoserine Lactone and Evaluation of Its Antiquorum Sensing Activity in Chromobacterium violaceum

DJ, Sanabria-Ríos; R, García-Del-Valle; S, Bosh-Fonseca; J, González-Pagán; A, Díaz-Rosa; K, Acevedo-Rosario; L, Reyes-Vicente; A, Colom; NM, Carballeira

Synthesis of the Novel N-(2-Hexadecynoyl)-l-Homoserine Lactone and Evaluation of Its Antiquorum Sensing Activity in Chromobacterium violaceum

In: ACS Omega, 2024.

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Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

JG, Medina-Feliciano; G, Valentín-Tirado; K, Luna-Martínez; Y, Miranda-Negrón; JE, García-Arrarás

Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

In: bioRxiv, 2024.

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 After an initial Hermansky-Pudlak syndrome clinical diagnosis, molecular testing reveals variants for oculocutaneous albinism type 1B: A case report

J, Serrano-González; I, Montes-Rodríguez; JY, Renta; R, Rojas; CL, Cadilla

After an initial Hermansky-Pudlak syndrome clinical diagnosis, molecular testing reveals variants for oculocutaneous albinism type 1B: A case report

In: Mol Genet Genomic Med, 2024.

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Unraveling the Impact of Six Pentacyclic Triterpenes Regulating Metabolic Pathways on Lung Carcinoma Cells

A, Torres-Sanchez; G, Torres; S, Estrada; D, Perez; C, Garcia; M, Milian; E, Velazquez; V, Molina; Y, Delgado

Unraveling the Impact of Six Pentacyclic Triterpenes Regulating Metabolic Pathways on Lung Carcinoma Cells

In: Pharmaceuticals (Basel), 2024.

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Plasma Proteins Associated with COVID-19 Severity in Puerto Rico

LJ, Rosario-Rodríguez; YM, Cantres-Rosario; K, Carrasquillo-Carrión; A, Rosa-Díaz; AE, Rodríguez-De Jesús; V, Rivera-Nieves; EL, Tosado-Rodríguez; LB, Méndez; A, Roche-Lima; J, Bertrán; LM, Meléndez

Plasma Proteins Associated with COVID-19 Severity in Puerto Rico

In: Int J Mol Sci, 2024.

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Improved LINE-1 Detection through Pattern Matching by Increasing Probe Length

JO, López; Quiñones J and, Martínez ED

Improved LINE-1 Detection through Pattern Matching by Increasing Probe Length

In: Biology (Basel), 2024.

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Quantitative Proteomics Reveal That CB2R Agonist JWH-133 Downregulates NF-κB Activation, Oxidative Stress, and Lysosomal Exocytosis from HIV-Infected Macrophages

LJ, Rosario-Rodríguez; YM, Cantres-Rosario; K, Carrasquillo-Carrión; AE, Rodríguez-De Jesús; LJ, Cartagena-Isern; LA, García-Requena; A, Roche-Lima; LM, Meléndez

Quantitative Proteomics Reveal That CB2R Agonist JWH-133 Downregulates NF-κB Activation, Oxidative Stress, and Lysosomal Exocytosis from HIV-Infected Macrophages

In: Int J Mol Sci, 2024.

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Advancing Primary Ciliary Dyskinesia Diagnosis through High-Speed Video Microscopy Analysis

W, De Jesús-Rojas; ZJ, Demetriou; J, Muñiz-Hernández; G, Rosario-Ortiz; FM, Quiñones; MJ, Ramos-Benitez; RA, Mosquera

Advancing Primary Ciliary Dyskinesia Diagnosis through High-Speed Video Microscopy Analysis

In: Cells, 2024.

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 Vaginal Microbiota and HPV in Latin America: A Narrative Review

E, Tosado-Rodríguez; I, Alvarado-Vélez; J, Romaguera; F, Godoy-Vitorino

Vaginal Microbiota and HPV in Latin America: A Narrative Review

In: Microorganisms, 2024.

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Gut microbiota composition is associated with the efficacy of Delta-24-RGDOX in malignant gliomas

NM, Meléndez-Vázquez; TT, Nguyen; X, Fan; AR, López-Rivas; J, Fueyo; C, Gomez-Manzano; F, Godoy-Vitorino

Gut microbiota composition is associated with the efficacy of Delta-24-RGDOX in malignant gliomas

In: Mol Ther Oncol, 2024.

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Estradiol reduction through aromatase inhibition impairs cocaine seeking in male rats

JK, Alvarado-Torres; R, Morales-Silva; de Leon A, Sanabria Ponce; G, Rodriguez-Torres; J, Perez-Torres; Y, Perez-Perez; D, Mueller; MT, Sepulveda-Orengo

Estradiol reduction through aromatase inhibition impairs cocaine seeking in male rats

In: Front Behav Neuroscience, 2024.

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Mechanistics of pH-Dependent Sulfmyoglobin Formation: Spin Control and His64 Proton Relay

Mackenzie, A.; Santos, L.; Arbelo, H.; Wymore, T.; Garriga, J.

Mechanistics of pH-Dependent Sulfmyoglobin Formation: Spin Control and His64 Proton Relay

In: Journal of Chemistry, vol. 2024, 2024.

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2023

In vitro generation of murine myeloid-derived suppressor cells from hematopoietic progenitor cells

LM, Hernandez-Delgado; A, Laboy-Figueroa; A, Lopez-Velazquez; C, Flores-Ortiz; K, Alicea-Torres

In vitro generation of murine myeloid-derived suppressor cells from hematopoietic progenitor cells

In: Methods Cell Biol, 2023.

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Inflammatory cytokines and a diverse cervicovaginal microbiota associate with cervical dysplasia in a cohort of Hispanics living in Puerto Rico

E, Tosado-Rodríguez; LB, Mendez; AM, Espino; S, Dorta-Estremera; EE, Aquino; J, Romaguera; F, Godoy-Vitorino

Inflammatory cytokines and a diverse cervicovaginal microbiota associate with cervical dysplasia in a cohort of Hispanics living in Puerto Rico

In: 2023.

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Determining the Safety of the Tobacco Cembranoid (1S,2E,4R,6R,7E,11E)-Cembratriene-4,6-diol (4R): A Translational Study in Nonhuman Primates

N, Sabeva; W, Castro; Y, Ferrer-Acosta; P.A, Ferchmin; V.A, Eterovic; D, Sierra-Mercado; N, Pérez-Rios; S, Rivas-Tumanyan; A.H, Martins

Determining the Safety of the Tobacco Cembranoid (1S,2E,4R,6R,7E,11E)-Cembratriene-4,6-diol (4R): A Translational Study in Nonhuman Primates

In: 2023.

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Evolutionary dynamics of genome size and content during the adaptive radiation of Heliconiini butterflies

F, Cicconardi; E, Milanetti; de Castro EC, Pinheiro; A, Mazo-Vargas; SM, Van Belleghem; AA, Ruggieri; P, Rastas; J, Hanly; E, Evans; CD, Jiggins; W, Owen McMillan; R, Papa; D, Di Marino; A, Martin; SH, Montgomery

Evolutionary dynamics of genome size and content during the adaptive radiation of Heliconiini butterflies

In: Nat Commun, 2023.

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The Characterization and Evaluation of the Soluble Triggering Receptor Expressed on Myeloid Cells-like Transcript-1 in Stable Coronary Artery Disease

Z, Bayrón-Marrero; S, Branfield; J, Menéndez-Pérez; Nieves-López B, Ospina L; Y, Cantres-Rosario; LM, Melendez; R, Hunter; A, Gibson; G, Maldonado-Martínez; AV, Washington

The Characterization and Evaluation of the Soluble Triggering Receptor Expressed on Myeloid Cells-like Transcript-1 in Stable Coronary Artery Disease

In: Int J Mol Sci., 2023.

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The cervical microbiota of Hispanics living in Puerto Rico is nonoptimal regardless of HPV status

D, Vargas-Robles; J, Romaguera; I, Alvarado-Velez; E, Tosado-Rodríguez; A, Dominicci-Maura; M, Sanchez; KJ, Wiggin; M, Martinez-Ferrer; JA, Gilbert; LJ, Forney; F, Godoy-Vitorino

The cervical microbiota of Hispanics living in Puerto Rico is nonoptimal regardless of HPV status

In: mSystems, 2023.

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Mechanisms of Regulation of the CHRDL1 Gene by the TWIST2 and ADD1/SREBP1c Transcription Factors

JJ, Casasnovas-Nieves; Y, Rodríguez; HL, Franco; CL, Cadilla

Mechanisms of Regulation of the CHRDL1 Gene by the TWIST2 and ADD1/SREBP1c Transcription Factors

In: Genes (Basel), 2023.

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Substrate topographies modulate the secretory activity of human bone marrow mesenchymal stem cells

H, Rosado-Galindo; M, Domenech

Substrate topographies modulate the secretory activity of human bone marrow mesenchymal stem cells

In: Stem Cell Res Ther, 2023.

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Assessment of Vibrio populations in a transect of Rhizophora mangle in Punta Galeta, Panamá: culture-dependent analyses reveal biotechnological applications

J, Sánchez-Gallego; L, Atencio; J, Pérez; O, Dupuy; E, Díaz-Ferguson; F, Godoy-Vitorino

Assessment of Vibrio populations in a transect of Rhizophora mangle in Punta Galeta, Panamá: culture-dependent analyses reveal biotechnological applications

In: Rev Biol Trop, 2023.

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Oncogenic Proteomics Approaches for Translational Research and HIV-Associated Malignancy Mechanisms

E, Alvarez-Rivera; EJ, Ortiz-Hernández; E, Lugo; LM, Lozada-Reyes; NM, Boukli

Oncogenic Proteomics Approaches for Translational Research and HIV-Associated Malignancy Mechanisms

In: Proteomes, 2023.

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Rac and Cdc42 inhibitors reduce macrophage function in breast cancer preclinical models

A, Torres-Sanchez; M, Rivera-Robles; L, Castillo-Pichardo; M, Martínez-Ferrer; SM, Dorta-Estremera; S, Dharmawardhane

Rac and Cdc42 inhibitors reduce macrophage function in breast cancer preclinical models

In: Front Oncol., 2023.

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The Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancer

Crespo GV, Ortiz J; EH, O'Farrill; CP, Vlaar; M, Inyushin; Y, Kucheryavykh; L, Kucheryavykh

The Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancer

2023.

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Gut microbiota variation of a tropical oil-collecting bee species far exceeds that of the honeybee

Kardas E,; AM, González-Rosario; T, Giray; JD, Ackerman; F, Godoy-Vitorino

Gut microbiota variation of a tropical oil-collecting bee species far exceeds that of the honeybee

In: Front Microbiol, 2023.

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SARS-CoV-2 Omicron Replacement of Delta as Predominant Variant, Puerto Rico

GA, Santiago; HR, Volkman; B, Flores; GL, González; KN, Charriez; LC, Huertas; SM, Van Belleghem; V, Rivera-Amill; C, Major; C, Colon; R, Tosado; LE, Adams; M, Marzán; L, Hernández; I, Cardona; E, O'Neill; G, Paz-Bailey; R, Papa; JL, Muñoz-Jordan

SARS-CoV-2 Omicron Replacement of Delta as Predominant Variant, Puerto Rico

In: Emerg Infect Dis., 2023.

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81 entries « 1 of 2 »